Separating Putative Pathogens from Background Contamination with Principal Orthogonal Decomposition: Evidence for Leptospira in the Ugandan Neonatal Septisome

Neonatal sepsis (NS) is responsible for over 1 million yearly deaths worldwide. In the developing world, NS is often treated without an identified microbial pathogen. Amplicon sequencing of the bacterial 16S rRNA gene can be used to identify organisms that are difficult to detect by routine microbio...

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Detalles Bibliográficos
Autores principales: Schiff, Steven J., Kiwanuka, Julius, Riggio, Gina, Nguyen, Lan, Mu, Kevin, Sproul, Emily, Bazira, Joel, Mwanga-Amumpaire, Juliet, Tumusiime, Dickson, Nyesigire, Eunice, Lwanga, Nkangi, Bogale, Kaleb T., Kapur, Vivek, Broach, James R., Morton, Sarah U., Warf, Benjamin C., Poss, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904006/
https://www.ncbi.nlm.nih.gov/pubmed/27379237
http://dx.doi.org/10.3389/fmed.2016.00022

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