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TIM-3 Regulates Distinct Functions in Macrophages
The transmembrane protein TIM-3 is a type I protein expressed by sub-types of lymphoid cells, such as lymphocytes Th1, Th17, Tc1, NK, as well as in myeloid cells. Scientific evidence indicates that this molecule acts as a negative regulator of T lymphocyte activation and that its expression is modif...
Autores principales: | Ocaña-Guzman, Ranferi, Torre-Bouscoulet, Luis, Sada-Ovalle, Isabel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904032/ https://www.ncbi.nlm.nih.gov/pubmed/27379093 http://dx.doi.org/10.3389/fimmu.2016.00229 |
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