Icariin Inhibits Pulmonary Hypertension Induced by Monocrotaline through Enhancement of NO/cGMP Signaling Pathway in Rats

It has been reported that icariin (ICA) increased contents of nitric oxide (NO) and cyclic guanosine monophosphate (cGMP) by improving expression of endothelial nitric oxide synthase (eNOS) and inhibition of phosphodiesterase type 5 (PDE5). In addition, dysfunction of the NO/cGMP pathway may play a...

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Detalles Bibliográficos
Autores principales: Li, Li-sheng, Luo, Yun-mei, Liu, Juan, Zhang, Yu, Fu, Xiao-xia, Yang, Dan-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904099/
https://www.ncbi.nlm.nih.gov/pubmed/27366192
http://dx.doi.org/10.1155/2016/7915415

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