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Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system

cAMP responsive element binding protein 3-like 3 (CREB3L3), a transcription factor expressed in the liver and small intestine, governs fasting-response energy homeostasis. Tissue-specific CREB3L3 knockout mice have not been generated till date. To our knowledge, this is the first study using the one...

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Detalles Bibliográficos
Autores principales:	Nakagawa, Yoshimi, Oikawa, Fusaka, Mizuno, Seiya, Ohno, Hiroshi, Yagishita, Yuka, Satoh, Aoi, Osaki, Yoshinori, Takei, Kenta, Kikuchi, Takuya, Han, Song-iee, Matsuzaka, Takashi, Iwasaki, Hitoshi, Kobayashi, Kazuto, Yatoh, Shigeru, Yahagi, Naoya, Isaka, Masaaki, Suzuki, Hiroaki, Sone, Hirohito, Takahashi, Satoru, Yamada, Nobuhiro, Shimano, Hitoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904192/ https://www.ncbi.nlm.nih.gov/pubmed/27291420 http://dx.doi.org/10.1038/srep27857

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