Mechanistic insights of O-GlcNAcylation that promote progression of cholangiocarcinoma cells via nuclear translocation of NF-κB

O-GlcNAcylation, an O-linked protein glycosylation with a single molecule of N-acetylglucosamine (GlcNAc), is reversibly controlled by O-GlcNAc transferase (OGT) and N-acetyl D-glucosaminidase (OGA). Aberrant O-GlcNAcylation contributes an important role in initiation and progression of many human c...

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Detalles Bibliográficos
Autores principales: Phoomak, Chatchai, Vaeteewoottacharn, Kulthida, Sawanyawisuth, Kanlayanee, Seubwai, Wunchana, Wongkham, Chaisiri, Silsirivanit, Atit, Wongkham, Sopit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904198/
https://www.ncbi.nlm.nih.gov/pubmed/27290989
http://dx.doi.org/10.1038/srep27853

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