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Luteolin inhibits GABA(A) receptors in HEK cells and brain slices

Modulation of the A type γ-aminobutyric acid receptors (GABA(A)R) is one of the major drug targets for neurological and psychological diseases. The natural flavonoid compound luteolin (2-(3,4-Dihydroxyphenyl)- 5,7-dihydroxy-4-chromenone) has been reported to have antidepressant, antinociceptive, and...

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Detalles Bibliográficos
Autores principales: Shen, Mei-Lin, Wang, Chen-Hung, Chen, Rita Yu-Tzu, Zhou, Ning, Kao, Shung-Te, Wu, Dong Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904371/
https://www.ncbi.nlm.nih.gov/pubmed/27292079
http://dx.doi.org/10.1038/srep27695

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