Cargando…
ZD7288, a selective hyperpolarization-activated cyclic nucleotide-gated channel blocker, inhibits hippocampal synaptic plasticity
The selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker 4-(N-ethyl-N-phenylamino)-1,2-dimethyl-6-(methylamino) pyrimidinium chloride (ZD7288) blocks the induction of long-term potentiation in the perforant path–CA3 region in rat hippocampus in vivo. To explore the mec...
Autores principales: | Zhang, Xiao-xue, Min, Xiao-chun, Xu, Xu-lin, Zheng, Min, Guo, Lian-jun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904469/ https://www.ncbi.nlm.nih.gov/pubmed/27335562 http://dx.doi.org/10.4103/1673-5374.182705 |
Ejemplares similares
-
The HCN Channel Blocker ZD7288 Induces Emesis in the Least Shrew (Cryptotis parva)
por: Zhong, W., et al.
Publicado: (2021) -
Differential expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits during hippocampal development in the mouse
por: Seo, Hyunhyo, et al.
Publicado: (2015) -
ZD7288, a blocker of the HCN channel family, increases doubling time of mouse embryonic stem cells and modulates differentiation outcomes in a context-dependent manner
por: Omelyanenko, Anna, et al.
Publicado: (2016) -
The Hyperpolarization-Activated Cyclic-Nucleotide-Gated Channel Blocker Ivabradine Does Not Prevent Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia
por: Bueno-Levy, Hanna, et al.
Publicado: (2020) -
ZD7288 Enhances Long-Term Depression at Early Postnatal Medial Perforant Path-Granule Cell Synapses
por: Guli, Xiati, et al.
Publicado: (2012)