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Thiopurines in the Management of Crohn's Disease: Safety and Efficacy Profile in Patients with Normal TPMT Activity—A Retrospective Study
Background and Aims. Thiopurines are used in the treatment of Crohn's disease (CD) and thiopurine S-methyltransferase (TPMT) activity can guide thiopurine dosing to avoid adverse events. This retrospective study evaluated the safety and efficacy of starting thiopurines at low dose versus full d...
Autores principales: | Benmassaoud, Amine, Xie, Xuanqian, AlYafi, Motaz, Theoret, Yves, Bitton, Alain, Afif, Waqqas, Bessissow, Talat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904638/ https://www.ncbi.nlm.nih.gov/pubmed/27446822 http://dx.doi.org/10.1155/2016/1034834 |
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