Cargando…

Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study

Self-expandable stents for obstructing colorectal cancer (CRC) offer an alternative to operative management. The objective of the study was to determine stent utilization for CRC obstruction in the province of Ontario between April 1, 2000, and March 30, 2009. Colonic stent utilization characteristi...

Descripción completa

Detalles Bibliográficos
Autores principales: Borowiec, Anna M., Wang, Charlie S. K., Yong, Elaine, Law, Calvin, Coburn, Natalie, Sutradhar, Rinku, Baxter, Nancy, Paszat, Lawrence, Tinmouth, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904648/
https://www.ncbi.nlm.nih.gov/pubmed/27446826
http://dx.doi.org/10.1155/2016/1945172
_version_ 1782437183410405376
author Borowiec, Anna M.
Wang, Charlie S. K.
Yong, Elaine
Law, Calvin
Coburn, Natalie
Sutradhar, Rinku
Baxter, Nancy
Paszat, Lawrence
Tinmouth, Jill
author_facet Borowiec, Anna M.
Wang, Charlie S. K.
Yong, Elaine
Law, Calvin
Coburn, Natalie
Sutradhar, Rinku
Baxter, Nancy
Paszat, Lawrence
Tinmouth, Jill
author_sort Borowiec, Anna M.
collection PubMed
description Self-expandable stents for obstructing colorectal cancer (CRC) offer an alternative to operative management. The objective of the study was to determine stent utilization for CRC obstruction in the province of Ontario between April 1, 2000, and March 30, 2009. Colonic stent utilization characteristics, poststent insertion health outcomes, and health care encounters were recorded. 225 patients were identified over the study period. Median age was 69 years, 2/3 were male, and 2/3 had metastatic disease. Stent use for CRC increased over the study period and gastroenterologists inserted most stents. The median survival after stent insertion was 199 (IQR, 69–834) days. 37% of patients required an additional procedure. Patients with metastatic disease were less likely to go on to surgery (HR 0.14, 95% CI 0.06–0.32, p < 0.0001). There were 2.4/person-year emergency department visits (95% CI 2.2–2.7) and 2.3 hospital admissions/person-year (95% CI 2.1–2.5) following stent insertion. Most admissions were cancer or procedure related or for palliation. Factors associated with hospital admissions were presence of metastatic disease, lack of chemotherapy treatment, and stoma surgery. Overall the use of stents for CRC obstruction remains low. Stents are predominantly used for palliation with low rates of postinsertion health care encounters.
format Online
Article
Text
id pubmed-4904648
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-49046482016-06-30 Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study Borowiec, Anna M. Wang, Charlie S. K. Yong, Elaine Law, Calvin Coburn, Natalie Sutradhar, Rinku Baxter, Nancy Paszat, Lawrence Tinmouth, Jill Can J Gastroenterol Hepatol Research Article Self-expandable stents for obstructing colorectal cancer (CRC) offer an alternative to operative management. The objective of the study was to determine stent utilization for CRC obstruction in the province of Ontario between April 1, 2000, and March 30, 2009. Colonic stent utilization characteristics, poststent insertion health outcomes, and health care encounters were recorded. 225 patients were identified over the study period. Median age was 69 years, 2/3 were male, and 2/3 had metastatic disease. Stent use for CRC increased over the study period and gastroenterologists inserted most stents. The median survival after stent insertion was 199 (IQR, 69–834) days. 37% of patients required an additional procedure. Patients with metastatic disease were less likely to go on to surgery (HR 0.14, 95% CI 0.06–0.32, p < 0.0001). There were 2.4/person-year emergency department visits (95% CI 2.2–2.7) and 2.3 hospital admissions/person-year (95% CI 2.1–2.5) following stent insertion. Most admissions were cancer or procedure related or for palliation. Factors associated with hospital admissions were presence of metastatic disease, lack of chemotherapy treatment, and stoma surgery. Overall the use of stents for CRC obstruction remains low. Stents are predominantly used for palliation with low rates of postinsertion health care encounters. Hindawi Publishing Corporation 2016 2016-03-29 /pmc/articles/PMC4904648/ /pubmed/27446826 http://dx.doi.org/10.1155/2016/1945172 Text en Copyright © 2016 Anna M. Borowiec et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Borowiec, Anna M.
Wang, Charlie S. K.
Yong, Elaine
Law, Calvin
Coburn, Natalie
Sutradhar, Rinku
Baxter, Nancy
Paszat, Lawrence
Tinmouth, Jill
Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title_full Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title_fullStr Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title_full_unstemmed Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title_short Colonic Stents for Colorectal Cancer Are Seldom Used and Mainly for Palliation of Obstruction: A Population-Based Study
title_sort colonic stents for colorectal cancer are seldom used and mainly for palliation of obstruction: a population-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904648/
https://www.ncbi.nlm.nih.gov/pubmed/27446826
http://dx.doi.org/10.1155/2016/1945172
work_keys_str_mv AT borowiecannam colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT wangcharliesk colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT yongelaine colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT lawcalvin colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT coburnnatalie colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT sutradharrinku colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT baxternancy colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT paszatlawrence colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy
AT tinmouthjill colonicstentsforcolorectalcancerareseldomusedandmainlyforpalliationofobstructionapopulationbasedstudy