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Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic Cardiomyopathy

Diabetic cardiomyopathy increases the risk of heart failure and death. At present, there are no effective approaches to preventing its development in the clinic. Here we report that reduction of cardiac GTP cyclohydrolase 1 (GCH1) degradation by genetic and pharmacological approaches protects the he...

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Detalles Bibliográficos
Autores principales:	Wu, Hsiang-En, Baumgardt, Shelley L., Fang, Juan, Paterson, Mark, Liu, Yanan, Du, Jianhai, Shi, Yang, Qiao, Shigang, Bosnjak, Zeljko J., Warltier, David C., Kersten, Judy R., Ge, Zhi-Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904741/ https://www.ncbi.nlm.nih.gov/pubmed/27295516 http://dx.doi.org/10.1038/srep27925

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