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Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan

Tumour blood vessels are gateways for distant metastasis. Recent studies have revealed that tumour endothelial cells (TECs) demonstrate distinct phenotypes from their normal counterparts. We have demonstrated that features of TECs are different depending on tumour malignancy, suggesting that TECs co...

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Detalles Bibliográficos
Autores principales: Maishi, Nako, Ohba, Yusuke, Akiyama, Kosuke, Ohga, Noritaka, Hamada, Jun-ichi, Nagao-Kitamoto, Hiroko, Alam, Mohammad Towfik, Yamamoto, Kazuyuki, Kawamoto, Taisuke, Inoue, Nobuo, Taketomi, Akinobu, Shindoh, Masanobu, Hida, Yasuhiro, Hida, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904795/
https://www.ncbi.nlm.nih.gov/pubmed/27295191
http://dx.doi.org/10.1038/srep28039