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Mighty mouse breakthroughs: a Sox2-driven model for squamous cell lung cancer

Squamous lung cancer is a subtype of non-small cell lung cancer with a poor overall prognosis. We have recently generated a mouse model of squamous lung carcinoma by overexpressing Sex-determining region Y-box 2 (Sox2) and deleting liver kinase B1 (Lkb1) using a lentiviral approach. This model recap...

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Detalles Bibliográficos
Autores principales:	Mukhopadhyay, Anandaroop, Oliver, Trudy G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Author'S View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904963/ https://www.ncbi.nlm.nih.gov/pubmed/27308419 http://dx.doi.org/10.4161/23723548.2014.969651

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