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A cancerous web: signaling, metabolism, and the epigenome

Histone acetylation is sensitive to the availability of acetyl-CoA. However, the extent to which metabolic alterations in cancer cells impact tumor histone acetylation has been unclear. Here, we discuss our recent findings that oncogenic AKT1 activation regulates histone acetylation levels in tumors...

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Detalles Bibliográficos
Autores principales:	Lee, Joyce V., Shah, Supriya, Carrer, Alessandro, Wellen, Kathryn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Author'S View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904988/ https://www.ncbi.nlm.nih.gov/pubmed/27308412 http://dx.doi.org/10.4161/23723548.2014.965620

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