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Discovery and validation of the antimetastatic activity of citalopram in colorectal cancer
Inverse gene expression profiling was recently shown to help drug repositioning. We showed that this approach works best for cancer and predicted novel drug candidates that may reduce metastasis in colorectal cancer. Antimetastatic activity of our predicted candidate, citalopram, was validated in an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4904995/ https://www.ncbi.nlm.nih.gov/pubmed/27308430 http://dx.doi.org/10.4161/23723556.2014.975080 |