Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53

Oxidative stress-induced sumoylation of TP53INP1 (tumor protein p53-induced nuclear protein 1) is essential to enhance the TP53 response. Sumoylation of TP53INP1 on the K113 residue, which is mediated by protein inhibitor of activated STAT 3 (PIAS3) and chromobox homolog 4 (CBX4) and removed by SUMO...

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Detalles Bibliográficos
Autores principales: Bonacci, Thomas, Peuget, Sylvain, Soubeyran, Philippe, Iovanna, Juan, Dusetti, Nelson J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905059/
https://www.ncbi.nlm.nih.gov/pubmed/27308354
http://dx.doi.org/10.4161/23723548.2014.964044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905059/
https://www.ncbi.nlm.nih.gov/pubmed/27308354
http://dx.doi.org/10.4161/23723548.2014.964044

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