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Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53
Oxidative stress-induced sumoylation of TP53INP1 (tumor protein p53-induced nuclear protein 1) is essential to enhance the TP53 response. Sumoylation of TP53INP1 on the K113 residue, which is mediated by protein inhibitor of activated STAT 3 (PIAS3) and chromobox homolog 4 (CBX4) and removed by SUMO...
Autores principales: | Bonacci, Thomas, Peuget, Sylvain, Soubeyran, Philippe, Iovanna, Juan, Dusetti, Nelson J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905059/ https://www.ncbi.nlm.nih.gov/pubmed/27308354 http://dx.doi.org/10.4161/23723548.2014.964044 |
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