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PTP1B: mediating ROS signaling to silence genes
Numerous studies have shown that normal cells often respond to the activation of oncogenes by undergoing reactive oxygen species-dependent induction of senescence. Here, we discuss our recent publication identifying protein tyrosine phosphatase PTP1B as an important redox-controlled checkpoint for s...
Autores principales: | Boivin, Benoit, Tonks, Nicholas K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905060/ https://www.ncbi.nlm.nih.gov/pubmed/27308433 http://dx.doi.org/10.4161/23723556.2014.975633 |
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