Oncogenic long noncoding RNA FAL1 in human cancer

Long non-coding RNAs (lncRNAs) are defined as RNA transcripts larger than 200 nucleotides that do not appear to have protein-coding potential. Accumulating evidence indicates that lncRNAs are involved in tumorigenesis. Our work reveals that lncRNA FAL1 (focally amplified lncRNA on chromosome 1) is f...

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Detalles Bibliográficos
Autores principales: Zhong, Xiaomin, Hu, Xiaowen, Zhang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author'S View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905162/
https://www.ncbi.nlm.nih.gov/pubmed/27308441
http://dx.doi.org/10.4161/23723556.2014.977154
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author Zhong, Xiaomin
Hu, Xiaowen
Zhang, Lin
author_facet Zhong, Xiaomin
Hu, Xiaowen
Zhang, Lin
author_sort Zhong, Xiaomin
collection PubMed
description Long non-coding RNAs (lncRNAs) are defined as RNA transcripts larger than 200 nucleotides that do not appear to have protein-coding potential. Accumulating evidence indicates that lncRNAs are involved in tumorigenesis. Our work reveals that lncRNA FAL1 (focally amplified lncRNA on chromosome 1) is frequently and focally amplified in human cancers and mediates oncogenic functions.
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spelling pubmed-49051622016-06-15 Oncogenic long noncoding RNA FAL1 in human cancer Zhong, Xiaomin Hu, Xiaowen Zhang, Lin Mol Cell Oncol Author'S View Long non-coding RNAs (lncRNAs) are defined as RNA transcripts larger than 200 nucleotides that do not appear to have protein-coding potential. Accumulating evidence indicates that lncRNAs are involved in tumorigenesis. Our work reveals that lncRNA FAL1 (focally amplified lncRNA on chromosome 1) is frequently and focally amplified in human cancers and mediates oncogenic functions. Taylor & Francis 2015-02-25 /pmc/articles/PMC4905162/ /pubmed/27308441 http://dx.doi.org/10.4161/23723556.2014.977154 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author'S View
Zhong, Xiaomin
Hu, Xiaowen
Zhang, Lin
Oncogenic long noncoding RNA FAL1 in human cancer
title Oncogenic long noncoding RNA FAL1 in human cancer
title_full Oncogenic long noncoding RNA FAL1 in human cancer
title_fullStr Oncogenic long noncoding RNA FAL1 in human cancer
title_full_unstemmed Oncogenic long noncoding RNA FAL1 in human cancer
title_short Oncogenic long noncoding RNA FAL1 in human cancer
title_sort oncogenic long noncoding rna fal1 in human cancer
topic Author'S View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905162/
https://www.ncbi.nlm.nih.gov/pubmed/27308441
http://dx.doi.org/10.4161/23723556.2014.977154
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AT zhanglin oncogeniclongnoncodingrnafal1inhumancancer

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