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ATM activation in hypoxia - causes and consequences
The DNA damage response is a complex signaling cascade that is triggered by cellular stress. This response is essential for the maintenance of genomic integrity and is considered to act as a barrier to the early stages of tumorigenesis. The integral role of ataxia telangiectasia mutated (ATM) kinase...
Autores principales: | Olcina, Monica M, Grand, Roger JA, Hammond, Ester M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905164/ https://www.ncbi.nlm.nih.gov/pubmed/27308313 http://dx.doi.org/10.4161/mco.29903 |
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