Aiolos and Lymphocyte Mimicry in Lung Cancer

Aggressive carcinomas tend to adopt behaviors normally restricted to lymphocytes, including anchorage-independent mobilization, response to chemokines, and modulation of local inflammatory conditions. In a recent study we identified the lymphocyte-restricted chromatin regulator Aiolos as an epigenet...

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Detalles Bibliográficos
Autores principales: Terada, Lance S, Liu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905172/
https://www.ncbi.nlm.nih.gov/pubmed/27308319
http://dx.doi.org/10.4161/mco.29912
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author Terada, Lance S
Liu, Zhe
author_facet Terada, Lance S
Liu, Zhe
author_sort Terada, Lance S
collection PubMed
description Aggressive carcinomas tend to adopt behaviors normally restricted to lymphocytes, including anchorage-independent mobilization, response to chemokines, and modulation of local inflammatory conditions. In a recent study we identified the lymphocyte-restricted chromatin regulator Aiolos as an epigenetic driver of lymphocyte mimicry in lung cancer that links immune cell development to metastatic behavior.
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spelling pubmed-49051722016-06-15 Aiolos and Lymphocyte Mimicry in Lung Cancer Terada, Lance S Liu, Zhe Mol Cell Oncol Review Aggressive carcinomas tend to adopt behaviors normally restricted to lymphocytes, including anchorage-independent mobilization, response to chemokines, and modulation of local inflammatory conditions. In a recent study we identified the lymphocyte-restricted chromatin regulator Aiolos as an epigenetic driver of lymphocyte mimicry in lung cancer that links immune cell development to metastatic behavior. Taylor & Francis 2014-07-28 /pmc/articles/PMC4905172/ /pubmed/27308319 http://dx.doi.org/10.4161/mco.29912 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Review
Terada, Lance S
Liu, Zhe
Aiolos and Lymphocyte Mimicry in Lung Cancer
title Aiolos and Lymphocyte Mimicry in Lung Cancer
title_full Aiolos and Lymphocyte Mimicry in Lung Cancer
title_fullStr Aiolos and Lymphocyte Mimicry in Lung Cancer
title_full_unstemmed Aiolos and Lymphocyte Mimicry in Lung Cancer
title_short Aiolos and Lymphocyte Mimicry in Lung Cancer
title_sort aiolos and lymphocyte mimicry in lung cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905172/
https://www.ncbi.nlm.nih.gov/pubmed/27308319
http://dx.doi.org/10.4161/mco.29912
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