Cargando…

HIPK2 modification code for cell death and survival

Homeodomain-interacting protein kinase 2 (HIPK2) is a serine/threonine protein kinase that participates in the regulation of diverse cellular activities as a transcriptional cofactor and signal transducer. HIPK2 senses various signaling cues that in turn phosphorylate downstream substrates to coordi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wook Choi, Dong, Yong Choi, Cheol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905192/ https://www.ncbi.nlm.nih.gov/pubmed/27308327 http://dx.doi.org/10.1080/23723548.2014.955999

Ejemplares similares

PARP1 regulates the protein stability and proapoptotic function of HIPK2
por: Choi, Jong-Ryoul, et al.
Publicado: (2016)

The Sweet Side of HIPK2
por: Garufi, Alessia, et al.
Publicado: (2023)

Role of HIPK2 in kidney fibrosis
por: Fan, Ying, et al.
Publicado: (2014)

p300-mediated acetylation increased the protein stability of HIPK2 and enhanced its tumor suppressor function
por: Choi, Jong-Ryoul, et al.
Publicado: (2017)

HIPK2 as a Novel Regulator of Fibrosis
por: Garufi, Alessia, et al.
Publicado: (2023)

Exercise downregulates HIPK2 and HIPK2 inhibition protects against myocardial infarction
por: Zhou, Qiulian, et al.
Publicado: (2021)

CircHIPK2 promotes proliferation of nasopharyngeal carcinoma by down-regulating HIPK2
por: Zhang, Dan, et al.
Publicado: (2022)

HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation
por: Verdina, Alessandra, et al.
Publicado: (2017)

Updates on HIPK2: a resourceful oncosuppressor for clearing cancer
por: D’Orazi, Gabriella, et al.
Publicado: (2012)

Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?
por: Stanga, Serena, et al.
Publicado: (2010)

Exosomal miR-1260b derived from non-small cell lung cancer promotes tumor metastasis through the inhibition of HIPK2
por: Kim, Dong Ha, et al.
Publicado: (2021)

Hyperglycemia triggers HIPK2 protein degradation
por: Baldari, Silvia, et al.
Publicado: (2016)

Transcriptional Corepressors HIPK1 and HIPK2 Control Angiogenesis Via TGF-β–TAK1–Dependent Mechanism
por: Shang, Yulei, et al.
Publicado: (2013)

Emerging landscape of circHIPK3 and its role in cancer and other diseases
por: Shao, Qi, et al.
Publicado: (2021)

HIPK2 in Angiogenesis: A Promising Biomarker in Cancer Progression and in Angiogenic Diseases
por: Garufi, Alessia, et al.
Publicado: (2023)

Interaction of Brn3a and HIPK2 mediates transcriptional repression of sensory neuron survival
por: Wiggins, Amanda K., et al.
Publicado: (2004)

Biogenesis, cellular effects, and biomarker value of circHIPK3
por: Fu, Yihan, et al.
Publicado: (2021)

HIPK4 is essential for murine spermiogenesis
por: Crapster, J Aaron, et al.
Publicado: (2020)

EGFR drives the progression of AKI to CKD through HIPK2 overexpression
por: Xu, Luyang, et al.
Publicado: (2019)

The Diagnostic and Therapeutic Role of Circular RNA HIPK3 in Human Diseases
por: Feng, Yanfei, et al.
Publicado: (2022)

Understanding the Dual Roles of CircHIPK3 in Tumorigenesis and Tumor Progression
por: Wei, Zeyu, et al.
Publicado: (2022)

Homeodomain-interacting protein kinase 2 (HIPK2): a promising target for anti-cancer therapies
por: Feng, Yuanyuan, et al.
Publicado: (2017)

Tubular HIPK2 is a key contributor to renal fibrosis
por: Xiao, Wenzhen, et al.
Publicado: (2020)

Exercise and cardioprotection: A “HIP” side of HIPK2 in the heart
por: Phrommintikul, Arintaya, et al.
Publicado: (2021)

Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses
por: Torrente, L, et al.
Publicado: (2017)

HIPK2 Phosphorylates the Microtubule-Severing Enzyme Spastin at S268 for Abscission
por: Pisciottani, Alessandra, et al.
Publicado: (2019)

Chromatin Targeting of HIPK2 Leads to Acetylation-Dependent Chromatin Decondensation
por: Haas, Jana, et al.
Publicado: (2020)

An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis
por: Gatti, Veronica, et al.
Publicado: (2020)

Inhibition of HIPK2 protects stress-induced pathological cardiac remodeling
por: Zhou, Qiulian, et al.
Publicado: (2022)

HIPK2 in the physiology of nervous system and its implications in neurological disorders
por: Sardina, F., et al.
Publicado: (2023)

Stress Granule Formation Attenuates RACK1-Mediated Apoptotic Cell Death Induced by Morusin
por: Park, Ye-Jin, et al.
Publicado: (2020)

SUMOylation modification-mediated cell death
por: Sheng, Zenghua, et al.
Publicado: (2021)

ASH2L Aggravates Fibrosis and Inflammation through HIPK2 in High Glucose-Induced Glomerular Mesangial Cells
por: Zhong, Wen, et al.
Publicado: (2022)

Apoptosis induced by a HIPK2 full-length-specific siRNA is due to off-target effects rather than prevalence of HIPK2-Δe8 isoform
por: Di Rocco, Giuliana, et al.
Publicado: (2015)

Double knock-out of Hmga1 and Hipk2 genes causes perinatal death associated to respiratory distress and thyroid abnormalities in mice
por: Gerlini, Raffaele, et al.
Publicado: (2019)

Sipi soup inhibits cancer-associated fibroblast activation and the inflammatory process by downregulating long non-coding RNA HIPK1-AS
por: Zhou, Bingxiu, et al.
Publicado: (2018)

Downregulation of HIPK2 Increases Resistance of Bladder Cancer Cell to Cisplatin by Regulating Wip1
por: Lin, Jun, et al.
Publicado: (2014)

Systems approach identifies HIPK2 as a critical regulator of kidney fibrosis
por: Jin, Yuanmeng, et al.
Publicado: (2012)

HIPK2 modulates p53 activity towards pro-apoptotic transcription
por: Puca, Rosa, et al.
Publicado: (2009)

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity
por: Valente, Davide, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_0grq7n847c91fuqfo0bbbggf95