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p53 isoforms change p53 paradigm
Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cell...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905211/ https://www.ncbi.nlm.nih.gov/pubmed/27308370 http://dx.doi.org/10.4161/23723548.2014.969136 |
| _version_ | 1782437229428211712 |
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| author | Bourdon, JC |
| author_facet | Bourdon, JC |
| author_sort | Bourdon, JC |
| collection | PubMed |
| description | Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cellular response to treatment. |
| format | Online Article Text |
| id | pubmed-4905211 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Taylor & Francis |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49052112016-06-15 p53 isoforms change p53 paradigm Bourdon, JC Mol Cell Oncol Author's View Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cellular response to treatment. Taylor & Francis 2014-12-31 /pmc/articles/PMC4905211/ /pubmed/27308370 http://dx.doi.org/10.4161/23723548.2014.969136 Text en © 2014 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
| spellingShingle | Author's View Bourdon, JC p53 isoforms change p53 paradigm |
| title | p53 isoforms change p53 paradigm |
| title_full | p53 isoforms change p53 paradigm |
| title_fullStr | p53 isoforms change p53 paradigm |
| title_full_unstemmed | p53 isoforms change p53 paradigm |
| title_short | p53 isoforms change p53 paradigm |
| title_sort | p53 isoforms change p53 paradigm |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905211/ https://www.ncbi.nlm.nih.gov/pubmed/27308370 http://dx.doi.org/10.4161/23723548.2014.969136 |
| work_keys_str_mv | AT bourdonjc p53isoformschangep53paradigm |