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p53 isoforms change p53 paradigm

Although p53 defines cellular responses to cancer treatment it is not clear how p53 can be used to control cell fate outcome. Data demonstrate that so-called p53 does not exist as a single protein, but is in fact a group of p53 protein isoforms whose expression can be manipulated to control the cell...

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Detalles Bibliográficos
Autor principal: Bourdon, JC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905211/
https://www.ncbi.nlm.nih.gov/pubmed/27308370
http://dx.doi.org/10.4161/23723548.2014.969136