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SIN3B, the SASP, and pancreatic cancer

Cellular senescence is classically considered a tumor suppressive mechanism. In addition to having stably exited the cell cycle, senescent cells secrete inflammatory factors. We recently demonstrated that senescence correlates with accelerated cancer progression in a mouse model of pancreatic ductal...

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Detalles Bibliográficos
Autores principales: Cantor, David J, David, Gregory
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905214/
https://www.ncbi.nlm.nih.gov/pubmed/27308374
http://dx.doi.org/10.4161/23723548.2014.969167

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