Porcine cancer models for translational oncology

Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorige...

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Detalles Bibliográficos
Autores principales: Sieren, Jessica C., Quelle, Dawn, Meyerholz, David K., Rogers, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905218/
https://www.ncbi.nlm.nih.gov/pubmed/27308376
http://dx.doi.org/10.4161/23723548.2014.969626
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author Sieren, Jessica C.
Quelle, Dawn
Meyerholz, David K.
Rogers, Christopher S.
author_facet Sieren, Jessica C.
Quelle, Dawn
Meyerholz, David K.
Rogers, Christopher S.
author_sort Sieren, Jessica C.
collection PubMed
description Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorigenesis in vivo through non-invasive clinical imaging approaches.
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spelling pubmed-49052182016-06-15 Porcine cancer models for translational oncology Sieren, Jessica C. Quelle, Dawn Meyerholz, David K. Rogers, Christopher S. Mol Cell Oncol Author's View Large-animal cancer models are needed to advance the development of innovative and clinically applicable tumor diagnostic, therapeutic, and monitoring technologies. We developed a genetically modified porcine model of cancer based on a TP53 mutation, and established its utility for tracking tumorigenesis in vivo through non-invasive clinical imaging approaches. Taylor & Francis 2014-11-11 /pmc/articles/PMC4905218/ /pubmed/27308376 http://dx.doi.org/10.4161/23723548.2014.969626 Text en © 2014 The Author(s). 2014 Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Sieren, Jessica C.
Quelle, Dawn
Meyerholz, David K.
Rogers, Christopher S.
Porcine cancer models for translational oncology
title Porcine cancer models for translational oncology
title_full Porcine cancer models for translational oncology
title_fullStr Porcine cancer models for translational oncology
title_full_unstemmed Porcine cancer models for translational oncology
title_short Porcine cancer models for translational oncology
title_sort porcine cancer models for translational oncology
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905218/
https://www.ncbi.nlm.nih.gov/pubmed/27308376
http://dx.doi.org/10.4161/23723548.2014.969626
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AT quelledawn porcinecancermodelsfortranslationaloncology
AT meyerholzdavidk porcinecancermodelsfortranslationaloncology
AT rogerschristophers porcinecancermodelsfortranslationaloncology

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