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Molecular mechanisms involved in initiation of the DNA damage response
DNA is subject to a wide variety of damage. In order to maintain genomic integrity, cells must respond to this damage by activating repair and cell cycle checkpoint pathways. The initiating events in the DNA damage response entail recognition of the lesion and the assembly of DNA damage response com...
Autores principales: | Barnum, Kevin J, O’Connell, Matthew J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905235/ https://www.ncbi.nlm.nih.gov/pubmed/27308403 http://dx.doi.org/10.4161/23723548.2014.970065 |
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