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The PBAF chromatin remodeling complex represses transcription and promotes rapid repair at DNA double-strand breaks
Transcription in the vicinity of DNA double-strand breaks (DSBs) is suppressed via a process involving ataxia telangiectasia mutated protein (ATM) and H2AK119 ubiquitylation.(1) We discuss recent findings that components of the Polybromo and Brahma-related gene 1 (BRG1)-associated factor (PBAF) remo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905236/ https://www.ncbi.nlm.nih.gov/pubmed/27308404 http://dx.doi.org/10.4161/23723548.2014.970072 |