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To live or let die – complexity within the E2F1 pathway

The E2F1 transcription factor is a recognized regulator of the cell cycle as well as a potent mediator of DNA damage-induced apoptosis and the checkpoint response. Understanding the diverse and seemingly dichotomous functions of E2F1 activity has been the focus of extensive ongoing research. Althoug...

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Detalles Bibliográficos
Autores principales: Poppy Roworth, A, Ghari, Fatemeh, La Thangue, Nicholas B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905241/
https://www.ncbi.nlm.nih.gov/pubmed/27308406
http://dx.doi.org/10.4161/23723548.2014.970480