TRPV1: Turning up the heat on intestinal tumorigenesis

TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstr...

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Detalles Bibliográficos
Autores principales: de Jong, Petrus R, Bertin, Samuel, Raz, Eyal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905246/
https://www.ncbi.nlm.nih.gov/pubmed/27308393
http://dx.doi.org/10.4161/23723556.2014.975619
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author de Jong, Petrus R
Bertin, Samuel
Raz, Eyal
author_facet de Jong, Petrus R
Bertin, Samuel
Raz, Eyal
author_sort de Jong, Petrus R
collection PubMed
description TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstream of epidermal growth factor receptor signaling that suppresses intestinal tumorigenesis.
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spelling pubmed-49052462016-06-15 TRPV1: Turning up the heat on intestinal tumorigenesis de Jong, Petrus R Bertin, Samuel Raz, Eyal Mol Cell Oncol Author's View TRP channels are associated with the development and progression of cancer but their precise molecular roles in these processes are unclear. Recently, we showed that the transient receptor potential cation channel, subfamily V, member 1 (TRPV1) ion channel is part of a negative feedback loop downstream of epidermal growth factor receptor signaling that suppresses intestinal tumorigenesis. Taylor & Francis 2014-12-01 /pmc/articles/PMC4905246/ /pubmed/27308393 http://dx.doi.org/10.4161/23723556.2014.975619 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
de Jong, Petrus R
Bertin, Samuel
Raz, Eyal
TRPV1: Turning up the heat on intestinal tumorigenesis
title TRPV1: Turning up the heat on intestinal tumorigenesis
title_full TRPV1: Turning up the heat on intestinal tumorigenesis
title_fullStr TRPV1: Turning up the heat on intestinal tumorigenesis
title_full_unstemmed TRPV1: Turning up the heat on intestinal tumorigenesis
title_short TRPV1: Turning up the heat on intestinal tumorigenesis
title_sort trpv1: turning up the heat on intestinal tumorigenesis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905246/
https://www.ncbi.nlm.nih.gov/pubmed/27308393
http://dx.doi.org/10.4161/23723556.2014.975619
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