Symmetry breaking in human neuroblastoma cells

Asymmetric cell division (ACD) is a characteristic of cancer stem cells, which exhibit high malignant potential. However, the cellular mechanisms that regulate symmetric (self-renewal) and asymmetric cell divisions are mostly unknown. Using human neuroblastoma cells, we found that the oncosuppressor...

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Detalles Bibliográficos
Autores principales: Izumi, Hideki, Kaneko, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905254/
https://www.ncbi.nlm.nih.gov/pubmed/27308367
http://dx.doi.org/10.4161/23723548.2014.968510
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author Izumi, Hideki
Kaneko, Yasuhiko
author_facet Izumi, Hideki
Kaneko, Yasuhiko
author_sort Izumi, Hideki
collection PubMed
description Asymmetric cell division (ACD) is a characteristic of cancer stem cells, which exhibit high malignant potential. However, the cellular mechanisms that regulate symmetric (self-renewal) and asymmetric cell divisions are mostly unknown. Using human neuroblastoma cells, we found that the oncosuppressor protein tripartite motif containing 32 (TRIM32) positively regulates ACD.
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spelling pubmed-49052542016-06-15 Symmetry breaking in human neuroblastoma cells Izumi, Hideki Kaneko, Yasuhiko Mol Cell Oncol Author's View Asymmetric cell division (ACD) is a characteristic of cancer stem cells, which exhibit high malignant potential. However, the cellular mechanisms that regulate symmetric (self-renewal) and asymmetric cell divisions are mostly unknown. Using human neuroblastoma cells, we found that the oncosuppressor protein tripartite motif containing 32 (TRIM32) positively regulates ACD. Taylor & Francis 2014-12-31 /pmc/articles/PMC4905254/ /pubmed/27308367 http://dx.doi.org/10.4161/23723548.2014.968510 Text en © 2014 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Izumi, Hideki
Kaneko, Yasuhiko
Symmetry breaking in human neuroblastoma cells
title Symmetry breaking in human neuroblastoma cells
title_full Symmetry breaking in human neuroblastoma cells
title_fullStr Symmetry breaking in human neuroblastoma cells
title_full_unstemmed Symmetry breaking in human neuroblastoma cells
title_short Symmetry breaking in human neuroblastoma cells
title_sort symmetry breaking in human neuroblastoma cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905254/
https://www.ncbi.nlm.nih.gov/pubmed/27308367
http://dx.doi.org/10.4161/23723548.2014.968510
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AT kanekoyasuhiko symmetrybreakinginhumanneuroblastomacells

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