Cargando…
p62: a hub of multiple signaling pathways in HER2-induced mammary tumorigenesis
We recently reported that depletion of p62 in the background of human epidermal growth factor receptor 2 (HER2) overexpression sensitizes mammary tumor cells to amino acid deprivation, abolishes cellular transformation in vitro, and suppresses mammary tumorigenesis in vivo. Extensive investigation o...
Autores principales: | Cai-McRae, Xiaofeng, Karantza, Vassiliki |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905285/ https://www.ncbi.nlm.nih.gov/pubmed/27308451 http://dx.doi.org/10.4161/23723556.2014.975035 |
Ejemplares similares
-
ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss
por: Lozy, Fred, et al.
Publicado: (2014) -
The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis
por: Liu, Yingying, et al.
Publicado: (2010) -
The interplay between autophagy and ROS in tumorigenesis
por: Kongara, Sameera, et al.
Publicado: (2012) -
Autophagy regulator BECN1 suppresses mammary tumorigenesis driven by WNT1 activation and following parity
por: Cicchini, Michelle, et al.
Publicado: (2014) -
p97 complexes as signal integration hubs
por: Meyer, Hemmo
Publicado: (2012)