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GD2 and GD3 synthase: novel drug targets for cancer therapy

Our recent study suggests that targeting GD3 synthase (also known as ST8SIA1)—the rate-limiting enzyme in biosynthesis of the breast cancer stem cell marker GD2—abrogates metastasis and depletes the cancer stem cell populations within a tumor, thus providing an effective therapeutic strategy against...

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Detalles Bibliográficos
Autores principales:	Sphyris, Nathalie, Sarkar, Tapasree Roy, Battula, Venkata L, Andreeff, Michael, Mani, Sendurai A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Author's Views
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905286/ https://www.ncbi.nlm.nih.gov/pubmed/27308452 http://dx.doi.org/10.4161/23723556.2014.975068

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