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Fateful music from a talented orchestra with a wicked conductor: Connection between oncogenic BRAF, ER stress, and autophagy in human melanoma

Autophagy and endoplasmic reticulum (ER) stress are involved in the development, progression, and chemoresistance of melanoma. We recently reported that oncogenic serine/threonine-protein kinase BRAF induces chronic ER stress, hence increasing baseline autophagy and promoting chemoresistance. The at...

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Detalles Bibliográficos
Autores principales: Giglio, Paola, Fimia, Gian Maria, Lovat, Penny E, Piacentini, Mauro, Corazzari, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905314/
https://www.ncbi.nlm.nih.gov/pubmed/27308477
http://dx.doi.org/10.4161/23723556.2014.995016