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Boosting NAD(+) for the prevention and treatment of liver cancer
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide yet has limited therapeutic options. We recently demonstrated that inhibition of de novo nicotinamide adenine dinucleotide (NAD(+)) synthesis is responsible for DNA damage, thereby initiating hepatocarcinogenesis. We...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905329/ https://www.ncbi.nlm.nih.gov/pubmed/27308492 http://dx.doi.org/10.1080/23723556.2014.1001199 |