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Boosting NAD(+) for the prevention and treatment of liver cancer

Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide yet has limited therapeutic options. We recently demonstrated that inhibition of de novo nicotinamide adenine dinucleotide (NAD(+)) synthesis is responsible for DNA damage, thereby initiating hepatocarcinogenesis. We...

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Detalles Bibliográficos
Autor principal: Djouder, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905329/
https://www.ncbi.nlm.nih.gov/pubmed/27308492
http://dx.doi.org/10.1080/23723556.2014.1001199