Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer

Inflammation and mutation of the tumor suppressor p53 are two apparently unrelated conditions that are strongly associated with cancer initiation and progression. We recently reported that gain-of-function mutant p53 modifies the response of cancer cells to inflammatory signals by binding a cytoplas...

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Detalles Bibliográficos
Autores principales: Bellazzo, Arianna, Di Minin, Giulio, Collavin, Licio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905342/
https://www.ncbi.nlm.nih.gov/pubmed/27308497
http://dx.doi.org/10.1080/23723556.2014.1002719
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author Bellazzo, Arianna
Di Minin, Giulio
Collavin, Licio
author_facet Bellazzo, Arianna
Di Minin, Giulio
Collavin, Licio
author_sort Bellazzo, Arianna
collection PubMed
description Inflammation and mutation of the tumor suppressor p53 are two apparently unrelated conditions that are strongly associated with cancer initiation and progression. We recently reported that gain-of-function mutant p53 modifies the response of cancer cells to inflammatory signals by binding a cytoplasmic tumor suppressor protein involved in TNFα signaling.
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spelling pubmed-49053422016-06-15 Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer Bellazzo, Arianna Di Minin, Giulio Collavin, Licio Mol Cell Oncol Author's View Inflammation and mutation of the tumor suppressor p53 are two apparently unrelated conditions that are strongly associated with cancer initiation and progression. We recently reported that gain-of-function mutant p53 modifies the response of cancer cells to inflammatory signals by binding a cytoplasmic tumor suppressor protein involved in TNFα signaling. Taylor & Francis 2015-01-23 /pmc/articles/PMC4905342/ /pubmed/27308497 http://dx.doi.org/10.1080/23723556.2014.1002719 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Bellazzo, Arianna
Di Minin, Giulio
Collavin, Licio
Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title_full Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title_fullStr Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title_full_unstemmed Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title_short Cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
title_sort cytoplasmic gain-of-function mutant p53 contributes to inflammation-associated cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905342/
https://www.ncbi.nlm.nih.gov/pubmed/27308497
http://dx.doi.org/10.1080/23723556.2014.1002719
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AT diminingiulio cytoplasmicgainoffunctionmutantp53contributestoinflammationassociatedcancer
AT collavinlicio cytoplasmicgainoffunctionmutantp53contributestoinflammationassociatedcancer

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