Linking apoptosis to cancer metabolism: Another missing piece of JuNK

Cancer cells become dependent on aerobic glycolysis to sustain rapid proliferation and escape apoptosis. How this metabolic change, also known as the Warburg effect, is linked to apoptosis remains largely unknown. Our new data place c-Jun N-terminal kinase in the center of a hub regulating apoptosis...

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Detalles Bibliográficos
Autores principales: Papa, Salvatore, Bubici, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905410/
https://www.ncbi.nlm.nih.gov/pubmed/27308628
http://dx.doi.org/10.1080/23723556.2015.1103398
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author Papa, Salvatore
Bubici, Concetta
author_facet Papa, Salvatore
Bubici, Concetta
author_sort Papa, Salvatore
collection PubMed
description Cancer cells become dependent on aerobic glycolysis to sustain rapid proliferation and escape apoptosis. How this metabolic change, also known as the Warburg effect, is linked to apoptosis remains largely unknown. Our new data place c-Jun N-terminal kinase in the center of a hub regulating apoptosis and cancer metabolism.
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spelling pubmed-49054102017-04-04 Linking apoptosis to cancer metabolism: Another missing piece of JuNK Papa, Salvatore Bubici, Concetta Mol Cell Oncol Author's View Cancer cells become dependent on aerobic glycolysis to sustain rapid proliferation and escape apoptosis. How this metabolic change, also known as the Warburg effect, is linked to apoptosis remains largely unknown. Our new data place c-Jun N-terminal kinase in the center of a hub regulating apoptosis and cancer metabolism. Taylor & Francis 2016-04-04 /pmc/articles/PMC4905410/ /pubmed/27308628 http://dx.doi.org/10.1080/23723556.2015.1103398 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License http://creativecommons.org/licenses/by-nc/3.0/, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Papa, Salvatore
Bubici, Concetta
Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title_full Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title_fullStr Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title_full_unstemmed Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title_short Linking apoptosis to cancer metabolism: Another missing piece of JuNK
title_sort linking apoptosis to cancer metabolism: another missing piece of junk
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905410/
https://www.ncbi.nlm.nih.gov/pubmed/27308628
http://dx.doi.org/10.1080/23723556.2015.1103398
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