Antitumor activity of LSD1 inhibitors in lung cancer

Epigenetic machinery have become a major focus for new targeted cancer therapies. Our previous report described the discovery and biological activity of a potent, selective, orally bioavailable, irreversible inhibitor of Lysine Demethylase 1 (LSD1), GSK2879552. A proliferation screen of cell lines r...

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Detalles Bibliográficos
Autores principales: Mohammad, Helai P., Kruger, Ryan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905412/
https://www.ncbi.nlm.nih.gov/pubmed/27308632
http://dx.doi.org/10.1080/23723556.2015.1117700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905412/
https://www.ncbi.nlm.nih.gov/pubmed/27308632
http://dx.doi.org/10.1080/23723556.2015.1117700

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