Emerging role of CD300 receptors in regulating myeloid cell efferocytosis

Engulfment of apoptotic cells is predominantly executed by phagocytes via the recognition of “eat me” signals like phosphatidylserine (PS). Various PS-specific receptors exist on phagocytes, including Tyro3, Axl, and MerTK receptor tyrosine kinases (TAMs), T-cell immunoglobulin and mucin domain cont...

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Autores principales: Voss, Oliver H, Tian, Linjie, Murakami, Yousuke, Coligan, John E, Krzewski, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905414/
https://www.ncbi.nlm.nih.gov/pubmed/27308512
http://dx.doi.org/10.4161/23723548.2014.964625
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author Voss, Oliver H
Tian, Linjie
Murakami, Yousuke
Coligan, John E
Krzewski, Konrad
author_facet Voss, Oliver H
Tian, Linjie
Murakami, Yousuke
Coligan, John E
Krzewski, Konrad
author_sort Voss, Oliver H
collection PubMed
description Engulfment of apoptotic cells is predominantly executed by phagocytes via the recognition of “eat me” signals like phosphatidylserine (PS). Various PS-specific receptors exist on phagocytes, including Tyro3, Axl, and MerTK receptor tyrosine kinases (TAMs), T-cell immunoglobulin and mucin domain containing 1 and 4 (TIM1/4), and the newly identified CD300 family. The aim of the present auto-commentary is to highlight recent findings regarding the Cd300lf and Cd300lb receptors and their emerging roles in the development of autoimmune disease.
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spelling pubmed-49054142016-06-15 Emerging role of CD300 receptors in regulating myeloid cell efferocytosis Voss, Oliver H Tian, Linjie Murakami, Yousuke Coligan, John E Krzewski, Konrad Mol Cell Oncol Author's View Engulfment of apoptotic cells is predominantly executed by phagocytes via the recognition of “eat me” signals like phosphatidylserine (PS). Various PS-specific receptors exist on phagocytes, including Tyro3, Axl, and MerTK receptor tyrosine kinases (TAMs), T-cell immunoglobulin and mucin domain containing 1 and 4 (TIM1/4), and the newly identified CD300 family. The aim of the present auto-commentary is to highlight recent findings regarding the Cd300lf and Cd300lb receptors and their emerging roles in the development of autoimmune disease. Taylor & Francis 2015-06-05 /pmc/articles/PMC4905414/ /pubmed/27308512 http://dx.doi.org/10.4161/23723548.2014.964625 Text en © 2015 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Voss, Oliver H
Tian, Linjie
Murakami, Yousuke
Coligan, John E
Krzewski, Konrad
Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title_full Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title_fullStr Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title_full_unstemmed Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title_short Emerging role of CD300 receptors in regulating myeloid cell efferocytosis
title_sort emerging role of cd300 receptors in regulating myeloid cell efferocytosis
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905414/
https://www.ncbi.nlm.nih.gov/pubmed/27308512
http://dx.doi.org/10.4161/23723548.2014.964625
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