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Reactive oxygen species and tumor dissemination: Allies no longer

For decades, reactive oxygen species (ROS) linked to oxidative stress have been suggested to promote carcinogenesis. However, we and others have demonstrated a protective role for ROS in metastatic dissemination. These recent studies partly explain the large failure observed in clinical trials using...

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Detalles Bibliográficos
Autores principales: Herraiz, Cecilia, Crosas-Molist, Eva, Sanz-Moreno, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905421/
https://www.ncbi.nlm.nih.gov/pubmed/27308633
http://dx.doi.org/10.1080/23723556.2015.1127313
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author Herraiz, Cecilia
Crosas-Molist, Eva
Sanz-Moreno, Victoria
author_facet Herraiz, Cecilia
Crosas-Molist, Eva
Sanz-Moreno, Victoria
author_sort Herraiz, Cecilia
collection PubMed
description For decades, reactive oxygen species (ROS) linked to oxidative stress have been suggested to promote carcinogenesis. However, we and others have demonstrated a protective role for ROS in metastatic dissemination. These recent studies partly explain the large failure observed in clinical trials using antioxidants for cancer prevention.
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spelling pubmed-49054212017-01-19 Reactive oxygen species and tumor dissemination: Allies no longer Herraiz, Cecilia Crosas-Molist, Eva Sanz-Moreno, Victoria Mol Cell Oncol Author's View For decades, reactive oxygen species (ROS) linked to oxidative stress have been suggested to promote carcinogenesis. However, we and others have demonstrated a protective role for ROS in metastatic dissemination. These recent studies partly explain the large failure observed in clinical trials using antioxidants for cancer prevention. Taylor & Francis 2016-01-19 /pmc/articles/PMC4905421/ /pubmed/27308633 http://dx.doi.org/10.1080/23723556.2015.1127313 Text en © 2016 The Author(s). Published with license by Taylor & Francis Group, LLC http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
spellingShingle Author's View
Herraiz, Cecilia
Crosas-Molist, Eva
Sanz-Moreno, Victoria
Reactive oxygen species and tumor dissemination: Allies no longer
title Reactive oxygen species and tumor dissemination: Allies no longer
title_full Reactive oxygen species and tumor dissemination: Allies no longer
title_fullStr Reactive oxygen species and tumor dissemination: Allies no longer
title_full_unstemmed Reactive oxygen species and tumor dissemination: Allies no longer
title_short Reactive oxygen species and tumor dissemination: Allies no longer
title_sort reactive oxygen species and tumor dissemination: allies no longer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905421/
https://www.ncbi.nlm.nih.gov/pubmed/27308633
http://dx.doi.org/10.1080/23723556.2015.1127313
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