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Speed matters: How subtle changes in DNA end resection rate affect repair
The contribution of BRCA1 (breast cancer 1) to the repair of broken DNA is well established, but its real role at the molecular level is less well understood. By developing a new high-resolution, single-molecule technique, we have now shown that BRCA1 accelerates the processing of DNA breaks that su...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905430/ https://www.ncbi.nlm.nih.gov/pubmed/27308460 http://dx.doi.org/10.4161/23723556.2014.982964 |