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MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency
Zinc deficiency (ZD) increases the risk of esophageal squamous cell carcinoma (ESCC), and marginal ZD is prevalent in humans. In rats, marked-ZD (3 mg Zn/kg diet) induces a proliferative esophagus with a 5-microRNA signature (miR-31, -223, -21, -146b, -146a) and promotes ESCC. Here we report that mo...
Autores principales: | Fong, Louise Y., Taccioli, Cristian, Jing, Ruiyan, Smalley, Karl J., Alder, Hansjuerg, Jiang, Yubao, Fadda, Paolo, Farber, John L., Croce, Carlo M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905434/ https://www.ncbi.nlm.nih.gov/pubmed/26918602 http://dx.doi.org/10.18632/oncotarget.7561 |
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