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Removal of regulatory T cells prevents secondary chronic infection but increases the mortality of subsequent sub-acute infection in sepsis mice
The immunosuppression following initial septic insult impairs resistance to secondary infection. Modulation of lymphocytes population may help to develop an effective therapeutic strategy. In this study, lipopolysaccharide (LPS)-induced endotoxemia was employed as the initial septic insult. 24 hours...
Autores principales: | Huo, Ruichao, Wang, Lili, Wang, Xiaoya, Zhao, Yong, Wang, Yi, Zhao, Xiaomin, Chang, Lingling, Liu, Shan-lu, Tong, Dewen, Zhang, Hai, Huang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905451/ https://www.ncbi.nlm.nih.gov/pubmed/26918357 http://dx.doi.org/10.18632/oncotarget.7682 |
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