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Aldehyde dehydrogenase 1A1 in stem cells and cancer

The human genome contains 19 putatively functional aldehyde dehydrogenase (ALDH) genes, which encode enzymes critical for detoxification of endogenous and exogenous aldehyde substrates through NAD(P)(+)-dependent oxidation. ALDH1 has three main isotypes, ALDH1A1, ALDH1A2, and ALDH1A3, and is a marke...

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Detalles Bibliográficos
Autores principales:	Tomita, Hiroyuki, Tanaka, Kaori, Tanaka, Takuji, Hara, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905455/ https://www.ncbi.nlm.nih.gov/pubmed/26783961 http://dx.doi.org/10.18632/oncotarget.6920

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