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Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome

Stem cell antigen-1 (Sca-1) is used to isolate and characterize tumor initiating cell populations from tumors of various murine models [1]. Sca-1 induced disruption of TGF-β signaling is required in vivo tumorigenesis in breast cancer models [2, 3-5]. The role of human Ly6 gene family is only beginn...

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Detalles Bibliográficos
Autores principales: Luo, Linlin, McGarvey, Peter, Madhavan, Subha, Kumar, Rakesh, Gusev, Yuriy, Upadhyay, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905465/
https://www.ncbi.nlm.nih.gov/pubmed/26862846
http://dx.doi.org/10.18632/oncotarget.7163

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