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Smad4-dependent suppressor pituitary homeobox 2 promotes PPP2R2A-mediated inhibition of Akt pathway in pancreatic cancer

The importance of Pituitary homeobox 2 (Pitx2) in malignancy remains enigmatic, and Pitx2 has not been previously implicated in pancreatic ductal adenocarcinoma (PDAC). In this study, we performed gene expression profiling of human PDAC tissues and identified Pitx2 as a promising candidate. Pitx2 ex...

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Detalles Bibliográficos
Autores principales:	Wang, Qi, Li, Juanjuan, Wu, Wei, Shen, Ruizhe, Jiang, He, Qian, Yuting, Tang, Yanping, Bai, Tingting, Wu, Sheng, Wei, Lumin, Zang, Yi, Zhang, Ji, Wang, Lifu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905467/ https://www.ncbi.nlm.nih.gov/pubmed/26848620 http://dx.doi.org/10.18632/oncotarget.7158

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