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HIF2α contributes to antiestrogen resistance via positive bilateral crosstalk with EGFR in breast cancer cells
The majority of breast cancers express estrogen receptor α (ERα), and most patients with ERα-positive breast cancer benefit from antiestrogen therapy. The ERα-modulator tamoxifen and ERα-downregulator fulvestrant are commonly employed antiestrogens. Antiestrogen resistance remains a clinical challen...
Autores principales: | Alam, Muhammad Wasi, Persson, Camilla Ulrika, Reinbothe, Susann, Kazi, Julhash U., Rönnstrand, Lars, Wigerup, Caroline, Ditzel, Henrik Jorn, Lykkesfeldt, Anne E., Påhlman, Sven, Jögi, Annika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905469/ https://www.ncbi.nlm.nih.gov/pubmed/26849233 http://dx.doi.org/10.18632/oncotarget.7167 |
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