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SIRT1 increases YAP- and MKK3-dependent p38 phosphorylation in mouse liver and human hepatocellular carcinoma

Both oncoprotein and tumor-suppressor activity have been reported for SIRTUIN1 (SIRT1) and p38 in many types of cancer. The effect of SIRT1 on p38 phosphorylation (p-p38) remains controversial and may be organ- and cell-specific. We found that SIRT1 is essential for maintaining liver size and weight...

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Detalles Bibliográficos
Autores principales:	Wang, Yulan, Cui, Ran, Zhang, Xiao, Qiao, Yongxia, Liu, Xiangfan, Chang, Yefei, Yu, Yongchun, Sun, Fenyong, Wang, Jiayi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905473/ https://www.ncbi.nlm.nih.gov/pubmed/26824501 http://dx.doi.org/10.18632/oncotarget.7022

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