Cargando…

Brachyury identifies a class of enteroendocrine cells in normal human intestinal crypts and colorectal cancer

Normal homeostasis of adult intestinal epithelium and repair following tissue damage is maintained by a balance of stem and differentiated cells, many of which are still only poorly characterised. Enteroendocrine cells of the gut are a small population of differentiated, secretory cells that are cri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jezkova, Jana, Williams, Jason S., Pinto, Filipe, Sammut, Stephen J., Williams, Geraint T., Gollins, Simon, McFarlane, Ramsay J., Reis, Rui Manuel, Wakeman, Jane A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905487/ https://www.ncbi.nlm.nih.gov/pubmed/26862851 http://dx.doi.org/10.18632/oncotarget.7202

Ejemplares similares

Brachyury regulates proliferation of cancer cells via a p27(Kip1-)dependent pathway
por: Jezkova, Jana, et al.
Publicado: (2014)

Enteroendocrine Cells Protect the Stem Cell Niche by Regulating Crypt Metabolism in Response to Nutrients
por: McCauley, Heather A., et al.
Publicado: (2023)

Involvement of the enteroendocrine system in intestinal obstruction
por: Ballouhey, Quentin, et al.
Publicado: (2017)

A novel cohort of cancer-testis biomarker genes revealed through meta-analysis of clinical data sets
por: Sammut, Stephen J., et al.
Publicado: (2014)

Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
por: Planells-Palop, Vicente, et al.
Publicado: (2017)

Involvement of Intestinal Enteroendocrine Cells in Neurological and Psychiatric Disorders
por: Yu, Liangen, et al.
Publicado: (2022)

Intestinal Enteroendocrine Cells: Present and Future Druggable Targets
por: Atanga, Roger, et al.
Publicado: (2023)

Brachyury as a potential modulator of androgen receptor activity and a key player in therapy resistance in prostate cancer
por: Pinto, Filipe, et al.
Publicado: (2016)

Enteroendocrine peptides, growth, and the microbiome during the porcine weaning transition
por: Ramsay, T. G., et al.
Publicado: (2022)

Human norovirus targets enteroendocrine epithelial cells in the small intestine
por: Green, Kim Y., et al.
Publicado: (2020)

An enteroendocrine-microbial axis in the large intestine controls host metabolism
por: Tan, Shuai, et al.
Publicado: (2023)

Lineage selection and plasticity in the intestinal crypt
por: Philpott, Anna, et al.
Publicado: (2014)

Identification of a class of human cancer germline genes with transcriptional silencing refractory to the hypomethylating drug 5-aza-2′-deoxycytidine.
por: Almatrafi, Ahmed, et al.
Publicado: (2014)

STUDIES ON SMALL INTESTINAL CRYPT EPITHELIUM : I. The Fine Structure of the Crypt Epithelium of the Proximal Small Intestine of Fasting Humans
por: Trier, Jerry S.
Publicado: (1963)

Conserved enhancers control notochord expression of vertebrate Brachyury
por: Kemmler, Cassie L., et al.
Publicado: (2023)

Role of Intestinal Bitter Sensing in Enteroendocrine Hormone Secretion and Metabolic Control
por: Xie, Cong, et al.
Publicado: (2018)

Robust differentiation of human enteroendocrine cells from intestinal stem cells
por: Zeve, Daniel, et al.
Publicado: (2022)

The role of mechanics in the growth and homeostasis of the intestinal crypt
por: Almet, A. A., et al.
Publicado: (2020)

Quantitative Dissection of the Proximal Ciona brachyury Enhancer
por: Shimai, Kotaro, et al.
Publicado: (2022)

Phase I, dose-escalation, clinical trial of MVA-Brachyury-TRICOM vaccine demonstrating safety and brachyury-specific T cell responses
por: Heery, Christopher R, et al.
Publicado: (2015)

Effects of Flavanols on Enteroendocrine Secretion
por: Grau-Bové, Carme, et al.
Publicado: (2020)

Conserved enhancer logic controls the notochord expression of vertebrate Brachyury
por: Kemmler, Cassie L., et al.
Publicado: (2023)

Crypt cell development in newborn rat small intestine
Publicado: (1985)

Effects of weaning on intestinal crypt epithelial cells in piglets
por: Yang, Huansheng, et al.
Publicado: (2016)

A New Role for Endocrine Cells in the Intestinal Crypt
por: Brubaker, Patricia L.
Publicado: (2023)

Brachyury, Foxa2 and the cis-Regulatory Origins of the Notochord
por: José-Edwards, Diana S., et al.
Publicado: (2015)

The Roles of Embryonic Transcription Factor BRACHYURY in Tumorigenesis and Progression
por: Chen, Ming, et al.
Publicado: (2020)

Brachyury engineers cardiac repair competent stem cells
por: Li, Mark, et al.
Publicado: (2020)

Signalling pathways involved in the detection of peptones by murine small intestinal enteroendocrine L-cells
por: Pais, Ramona, et al.
Publicado: (2016)

Bacterial Metabolite Indole Modulates Incretin Secretion from Intestinal Enteroendocrine L Cells
por: Chimerel, Catalin, et al.
Publicado: (2014)

Local Control of Intestinal Stem Cell Homeostasis by Enteroendocrine Cells in the Adult Drosophila Midgut
por: Scopelliti, Alessandro, et al.
Publicado: (2014)

Enteroendocrine-derived glucagon-like peptide-2 controls intestinal amino acid transport
por: Lee, Jennifer, et al.
Publicado: (2017)

Transcription Factor Antagonism Controls Enteroendocrine Cell Specification from Intestinal Stem Cells
por: Li, Yumei, et al.
Publicado: (2017)

The Intestinal Fatty Acid-Enteroendocrine Interplay, Emerging Roles for Olfactory Signaling and Serotonin Conjugates
por: Meijerink, Jocelijn
Publicado: (2021)

Pharmacology and physiology of gastrointestinal enteroendocrine cells
por: Mace, O J, et al.
Publicado: (2015)

Enteroendocrine Dysfunction in Two Saudi Sisters
por: Ahmed, Amna Basheer M., et al.
Publicado: (2021)

Tau expression and phosphorylation in enteroendocrine cells
por: Chapelet, Guillaume, et al.
Publicado: (2023)

Colorectal Cancers Mimic Structural Organization of Normal Colonic Crypts
por: Cernat, Laura, et al.
Publicado: (2014)

Application of Three-Dimensional Imaging to the Intestinal Crypt Organoids and Biopsied Intestinal Tissues
por: Chen, Yun, et al.
Publicado: (2013)

Crypt restricted heterogeneity of goblet cell mucus glycoprotein in histologically normal human colonic mucosa: a potential marker of somatic mutation.
por: Fuller, C. E., et al.
Publicado: (1990)

Cannot write session to /tmp/vufind_sessions/sess_ru9n9e1h5vlagqhqgm7h2jobrp