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HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling

Hypoxic environment is critical in colorectal cancer (CRC) development. Most studies have mainly focused on hypoxia-inducible factor (HIF)-1α and HIF-2α as the major hypoxic transcription factors in CRC development and progression. However, the role of HIF-3α in CRC is not clear. Here we found that...

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Detalles Bibliográficos
Autores principales: Xue, Xiang, Jungles, Kylie, Onder, Gunseli, Samhoun, Jalal, Győrffy, Balázs, Hardiman, Karin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905494/
https://www.ncbi.nlm.nih.gov/pubmed/26871465
http://dx.doi.org/10.18632/oncotarget.7272