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HIF-3α1 promotes colorectal tumor cell growth by activation of JAK-STAT3 signaling
Hypoxic environment is critical in colorectal cancer (CRC) development. Most studies have mainly focused on hypoxia-inducible factor (HIF)-1α and HIF-2α as the major hypoxic transcription factors in CRC development and progression. However, the role of HIF-3α in CRC is not clear. Here we found that...
Autores principales: | Xue, Xiang, Jungles, Kylie, Onder, Gunseli, Samhoun, Jalal, Győrffy, Balázs, Hardiman, Karin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905494/ https://www.ncbi.nlm.nih.gov/pubmed/26871465 http://dx.doi.org/10.18632/oncotarget.7272 |
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